Yangwa:GroupIntro

From yangwa

πŸ‘‹ Welcome to the Lab of Synthetic Biopharmaceutics

We are a multidisciplinary team working at the intersection of **synthetic biology**, **DNA/RNA nanotechnology**, and **targeted drug delivery**. Our mission is to develop programmable molecular systems for precision immunotherapy and intracellular control.


🧠 Research Focus

πŸ‘©β€πŸ”¬ Lab Members

Dr. Yang Wang
Principal Investigator
DNA nanomedicine, synthetic biology
πŸ“§ yangwa@yourlab.org
Guangneng Xie
PhD Student
RNA origami, immune circuits
Anran Xu
PhD Student
DNA origami integrity, blood-based detection
Kang Wang
Research Assistant
T cell therapy, CAF targeting

πŸ“„ Selected Publications

  • **Wang Y**, et al. Infinite Molecular Networking: pH-Gated Peptide-DNA Chain Assembly for Death Receptor Activation. Nature Nanotechnology, 2025.
  • **Xie G**, Wang Y. RNA Origami Logic Circuits for Controlled Immune Cell Activation. Science Advances, 2024.
  • **Xu A**, et al. In Vivo Proximity Ligation Assay for Wireframe DNA Origami. ACS Nano, 2024.
  • **Wang Y**, Wu M-R. CAF-Targeted Aptamer-Antibody Cascades for Gated T Cell Engagement. Nature Biomedical Engineering, 2024.

🧭 Lab Highlights

  • πŸ† NSFC-STINT International Collaboration Grant Awarded (2024–2027)
  • ✈️ Academic visit to Sichuan University (Nov 2024)
  • πŸ”¬ Ongoing: Tornado RNA circuits in CAR-T cells
  • 🧬 Launch of LabWiki Platform (2025)

πŸ“ž Contact


πŸ“… This page was last updated on 2025/07/3.