SynBio Pharmaceutical Lab

We engineer programmable therapeutic systems at the intersection of synthetic biology and nucleic acid nanotechnology.

合成生物药物实验室专注于可编程治疗策略的构建，融合 DNA/RNA origami、基因电路与药物递送系统，推动精准药物与未来药剂学的发展。

Lab Members

王蛘

PI / Professor

谢广能

Graduate Student

徐安然

Graduate Student

Wang Yang, Igor Baars, ... A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns. Nature Nanotechnology. 19, 1366–1374 (2024)
Ioanna Smyrlaki, ... Wang Yang, ... Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch. Nature Communications. 15, 465 (2024)
Marco Lolaico, ... Wang Yang, ... Computer-Aided Design of A-Trail Routed Wireframe DNA. ACS Nano. 17, 6565–6574 (2023)
Miao Deng, ... Wang Yang, ... Curbing Exosome Communications. Advanced Materials. 35, 2303736 (2023)
Jiaye Liu#, Wang Yang# ... Pancreatic tumor eradication via selective Pin1 inhibition. Nature Communications. 13, 4308 (2022)
Keying Zhu, Wang Yang, ... Myeloid cell-specific topoisomerase 1 inhibition. EMBO Reports. 23: e54499 (2022)
Wang Yang, Erik Benson, ... DNA Origami Penetration in Cell Spheroid Models. Advanced Materials. 33, 2008457 (2021)
Wang Yang, Igor Baars, ... Clustering of Death Receptor for Apoptosis. ACS Nano. 15, 9614–9626 (2021)
Toon Verheyen, Wang Yang, ... Spatial organization-dependent EphA2 transcriptional responses. Nucleic Acid Research. 48, 5777–5787 (2020)

Address: 成都市人民南路三段四川大学华西药学院
Email: yang.wang@ki.se