Group Introduction: Difference between revisions
No edit summary |
No edit summary |
||
| Line 58: | Line 58: | ||
<strong>A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns</strong>. | <strong>A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns</strong>. | ||
<em style="color: #007BFF;">Nature Nanotechnology</em>. 19, pages1366–1374 (2024) | <em style="color: #007BFF;">Nature Nanotechnology</em>. 19, pages1366–1374 (2024) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 64: | Line 63: | ||
<strong>Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force</strong>. | <strong>Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force</strong>. | ||
<em style="color: #007BFF;">Nature Communications</em>. 15, 465 (2024) | <em style="color: #007BFF;">Nature Communications</em>. 15, 465 (2024) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 70: | Line 68: | ||
<strong>Computer-Aided Design of A-Trail Routed Wireframe DNA Nanostructures with Square Lattice Edges</strong>. | <strong>Computer-Aided Design of A-Trail Routed Wireframe DNA Nanostructures with Square Lattice Edges</strong>. | ||
<em style="color: #007BFF;">ACS Nano</em>. 17, 6565–6574 (2023) | <em style="color: #007BFF;">ACS Nano</em>. 17, 6565–6574 (2023) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 76: | Line 73: | ||
<strong>Curbing Exosome Communications for Metastatic Pancreatic Cancer Therapy</strong>. | <strong>Curbing Exosome Communications for Metastatic Pancreatic Cancer Therapy</strong>. | ||
<em style="color: #007BFF;">Advanced Materials</em>. 35, 2303736 (2023) | <em style="color: #007BFF;">Advanced Materials</em>. 35, 2303736 (2023) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 82: | Line 78: | ||
<strong>Pancreatic tumor eradication via selective Pin1 inhibition in CAFs and T cells</strong>. | <strong>Pancreatic tumor eradication via selective Pin1 inhibition in CAFs and T cells</strong>. | ||
<em style="color: #007BFF;">Nature Communications</em>. 13, 4308 (2022) | <em style="color: #007BFF;">Nature Communications</em>. 13, 4308 (2022) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 88: | Line 83: | ||
<strong>Myeloid-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation</strong>. | <strong>Myeloid-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation</strong>. | ||
<em style="color: #007BFF;">EMBO Reports</em>. 23: e54499 (2022) | <em style="color: #007BFF;">EMBO Reports</em>. 23: e54499 (2022) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 94: | Line 88: | ||
<strong>DNA Origami Penetration in Cell Spheroid Models Enhanced by Wireframe Design</strong>. | <strong>DNA Origami Penetration in Cell Spheroid Models Enhanced by Wireframe Design</strong>. | ||
<em style="color: #007BFF;">Advanced Materials</em>. 33, 2008457 (2021) | <em style="color: #007BFF;">Advanced Materials</em>. 33, 2008457 (2021) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 100: | Line 93: | ||
<strong>Clustering of Death Receptor for Apoptosis Using Nanoscale Patterns of Peptides</strong>. | <strong>Clustering of Death Receptor for Apoptosis Using Nanoscale Patterns of Peptides</strong>. | ||
<em style="color: #007BFF;">ACS Nano</em>. 15, 9614–9626 (2021) | <em style="color: #007BFF;">ACS Nano</em>. 15, 9614–9626 (2021) | ||
</li> | </li> | ||
<li> | <li> | ||
| Line 106: | Line 98: | ||
<strong>Spatial organization-dependent EphA2 transcriptional responses</strong>. | <strong>Spatial organization-dependent EphA2 transcriptional responses</strong>. | ||
<em style="color: #007BFF;">Nucleic Acid Research</em>. 48, 5777–5787 (2020) | <em style="color: #007BFF;">Nucleic Acid Research</em>. 48, 5777–5787 (2020) | ||
</li> | </li> | ||
</ol> | </ol> | ||
</div> | </div> | ||
</div> | </div> | ||
Revision as of 14:26, 19 April 2025
SynBio Pharmaceutical Lab
We engineer programmable therapeutic systems at the intersection of synthetic biology and nucleic acid nanotechnology.
合成生物药物实验室专注于可编程治疗策略的构建，融合 DNA/RNA origami、基因电路与药物递送系统，推动精准药物与未来药剂学的发展。
Lab Members
<img src="/path/to/wangyang.jpg" alt="Wang Yang" style="width: 120px; height: 120px; border-radius: 50%; object-fit: cover;">
王蛘
Professor, PI
<img src="/path/to/xieguangneng.jpg" alt="谢广能" style="width: 120px; height: 120px; border-radius: 50%; object-fit: cover;">
谢广能
Graduate Student
<img src="/path/to/xuanran.jpg" alt="徐安然" style="width: 120px; height: 120px; border-radius: 50%; object-fit: cover;">
徐安然
Graduate Student
Team Photo
<img src="/path/to/team-photo.jpg" alt="Group Photo" style="max-width: 100%; border-radius: 12px;">
Contact
Address: [Your Lab Address Here]
Email: [youremail@example.com]
Tel: +[Your Phone Number]
Collaborators
<img src="/path/to/institute1-logo.png" alt="Institute 1" style="height: 60px;"> <img src="/path/to/institute2-logo.png" alt="Institute 2" style="height: 60px;">
Publications
- Wang Yang, Igor Baars, ... A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns. Nature Nanotechnology. 19, pages1366–1374 (2024)
- Ioanna Smyrlaki, Ferenc Fördős, ... Wang Yang, ... Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force. Nature Communications. 15, 465 (2024)
- Marco Lolaico, ... Wang Yang, Björn Högberg*. Computer-Aided Design of A-Trail Routed Wireframe DNA Nanostructures with Square Lattice Edges. ACS Nano. 17, 6565–6574 (2023)
- Miao Deng, Rong Guo, Wang Yang, ... Curbing Exosome Communications for Metastatic Pancreatic Cancer Therapy. Advanced Materials. 35, 2303736 (2023)
- Jiaye Liu#, Wang Yang# ... Pancreatic tumor eradication via selective Pin1 inhibition in CAFs and T cells. Nature Communications. 13, 4308 (2022)
- Keying Zhu, Wang Yang, ... Myeloid-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation. EMBO Reports. 23: e54499 (2022)
- Wang Yang, Erik Benson, ... DNA Origami Penetration in Cell Spheroid Models Enhanced by Wireframe Design. Advanced Materials. 33, 2008457 (2021)
- Wang Yang, Igor Baars, ... Clustering of Death Receptor for Apoptosis Using Nanoscale Patterns of Peptides. ACS Nano. 15, 9614–9626 (2021)
- Toon Verheyen, Wang Yang, ... Spatial organization-dependent EphA2 transcriptional responses. Nucleic Acid Research. 48, 5777–5787 (2020)