Revision as of 20:44, 18 April 2025

SynBio Pharmaceutical Lab

We are a synthetic biology research group committed to engineering programmable therapeutic systems.

合成生物药物实验室聚焦于可编程治疗系统的开发，融合 DNA/RNA 折纸技术、基因电路设计与智能药物递送体系，致力于解决重大疾病的治疗瓶颈，推动精准药物与未来药剂学的前沿发展。

Lab Members

     <img src="/path/to/wangyang.jpg" alt="Wang Yang" style="width: 120px; height: 120px; border-radius: 50%; object-fit: cover;">

王蛘

Professor, PI

     <img src="/path/to/xieguangneng.jpg" alt="谢广能" style="width: 120px; height: 120px; border-radius: 50%; object-fit: cover;">

谢广能

Graduate Student

     <img src="/path/to/xuanran.jpg" alt="徐安然" style="width: 120px; height: 120px; border-radius: 50%; object-fit: cover;">

徐安然

Graduate Student

Publications

Wang Yang, Igor Baars, Ieva Berzina, Iris Rocamonde-Lago, Boxuan Shen, Yunshi Yang, Marco Lolaico, Janine Waldvogel, Ioanna Smyrlaki, Keying Zhu, Robert A Harris, Björn Högberg*. A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns. Nature Nanotechnology. 19, pages1366–1374 (2024)
Ioanna Smyrlaki, Ferenc Fördős, Iris Rocamonde-Lago, Wang Yang, Boxuan Shen, Antonio Lentini, Vincent C Luca, Björn Reinius, Ana I Teixeira, Björn Högberg*. Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force. Nature Communications. 15, Article number: 465 (2024).

For a complete list of publications, please visit our <a href="/index.php?title=Publications" style="color: #007BFF; text-decoration: none;">Publications Page</a>.

Contact

   Address: [Your Lab Address Here]

   Email: <a href="mailto:youremail@example.com" style="color: #007BFF;">youremail@example.com</a>

   Tel: +[Your Phone Number]

Collaborators

   <img src="/path/to/institute1-logo.png" alt="Institute 1" style="height: 60px;">
   <img src="/path/to/institute2-logo.png" alt="Institute 2" style="height: 60px;">

@@ Line 38: / Line 38: @@
        </li>
        <li>
-         Wang Y, Wu M-R, et al. <strong>Computational Antibody-Aptamer Logic Gates Direct T Cell Activation in Pancreatic Cancer</strong>. <em>Nature Biotechnology</em>. 2025;43(2):120–128.
+         Ioanna Smyrlaki, Ferenc Fördős, Iris Rocamonde-Lago, <span style="color: #007BFF;">Wang Yang</span>, Boxuan Shen, Antonio Lentini, Vincent C Luca, Björn Reinius, Ana I Teixeira, Björn Högberg*. <strong>Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force</strong>. <em>Nature Communications</em>. 15, Article number: 465 (2024).
        </li>
      </ol>