Group Introduction: Difference between revisions
(Created page with "<html> <!-- 顶部标题 --> <h1 style="text-align: center; font-size: 36px; margin-top: 20px; margin-bottom: 10px; color: #000;"> Synthetic BioPharmaceutics Group </h1> <p style="text-align: center; font-size: 18px; margin-bottom: 30px; color: #444;"> （合成生物药剂学课题组） </p> <style> body { font-family: 'Segoe UI', sans-serif; background-color: #ffffff; color: #000000; } h2 { margin-top: 40px;...") |
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<h4>Yang Wang 王蛘</h4> | <h4>Yang Wang 王蛘</h4> | ||
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<li><b>Wang Y</b>, et al. Programmable DNA robot for cancer therapy. <i>Nature Nanotechnology</i>, 2024.</li> | <li><b>Wang Y</b>, et al. Programmable DNA robot for cancer therapy. <i>Nature Nanotechnology</i>, 2024.</li> | ||
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Revision as of 16:23, 14 April 2025
Synthetic BioPharmaceutics Group
（合成生物药剂学课题组）
🔬 Research Focus
DNA/RNA Origami for Therapy
Design of 2D and 3D DNA/RNA nanostructures to deliver siRNA, aptamers, and proteins with precise spatial control and responsiveness to tumor cues.Logic-Gated Immune Activation
We engineer aptamer–antibody logic systems and RNA circuits that enable conditional T cell activation within immunosuppressive tumor environments.Peptide–DNA Conjugates for Receptor Clustering
We create pH-responsive peptide–DNA materials that self-assemble in acidic tumor microenvironments to cluster death receptors (e.g., TRAIL-R) and induce apoptosis.👤 Current Members
Yang Wang 王蛘
Xie Guangneng 谢广能
Student 研究生
Xu Anran 徐安然
PhD Student 研究生
Zhang Wei
Master Student
Li Jie
Intern
📚 Selective Publications 代表性论文
- Wang Y, et al. Programmable DNA robot for cancer therapy. Nature Nanotechnology, 2024.
📞 Contact
📍 West China School of Pharmacy, Sichuan University
📧 13547820971@163.com