Yangwa:GroupIntro: Difference between revisions
No edit summary |
No edit summary |
||
| Line 144: | Line 144: | ||
</div> | </div> | ||
<!-- 📚 | <!-- 📚 Publications --> | ||
<h2 id="publications">📚 Publications</h2> | <h2 id="publications">📚 Selective Publications 代表性论文</h2> | ||
<ul> | <ul> | ||
Revision as of 04:17, 12 April 2025
Synthetic BioPharmaceutics Group
（合成生物药剂学课题组）
🔬 Research Focus
DNA/RNA Origami for Therapy
Design of 2D and 3D DNA/RNA nanostructures to deliver siRNA, aptamers, and proteins with precise spatial control and responsiveness to tumor cues.Logic-Gated Immune Activation
We engineer aptamer–antibody logic systems and RNA circuits that enable conditional T cell activation within immunosuppressive tumor environments.Peptide–DNA Conjugates for Receptor Clustering
We create pH-responsive peptide–DNA materials that self-assemble in acidic tumor microenvironments to cluster death receptors (e.g., TRAIL-R) and induce apoptosis.👤 Current Members
Yang Wang 王蛘
Professor 海纳特聘教授(特聘研究员)
国家级青年人才
Xie Guangneng 谢广能
Student 研究生
Xu Anran 徐安然
PhD Student 研究生
Zhang Wei
Master Student
Li Jie
Intern
📚 Selective Publications 代表性论文
- Wang Y, et al. Programmable DNA robot for cancer therapy. Nature Nanotechnology, 2024.
- Wang Y, et al. RNA origami logic gates for T cell activation. Nature Biomedical Engineering, 2023.
📞 Contact
📍 West China School of Pharmacy, Sichuan University
📧 yangwa@lab.edu